Cortisol Is A Steroid Hormone That Can Pass Through The Plasma Membrane

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Cortisol Is A Steroid Hormone That Can Pass Through The Plasma Membrane

. Complete the flowchart describing the interaction of cortisol with intracellular receptors.
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1. Cortisol passes through the plasma membrane into the cytoplasm. 2. Cortisol-receptor complex forms in the cytoplasm. 3. Cortisol-receptor complex enters the nucleus where it binds to genes. 4. Cortisol-receptor complex acts as a transcription factor 5. The transcribed mRNA is translated into a specific protein. Cortisol is a small, hydrophobic steroid hormone that can pass through the plasma membrane of cells. In target cells, cortisol binds to the intracellular receptor protein in the cytoplasm, forming a hormone-receptor complex. The hormone-receptor complex then moves into the nucleus and acts as a transcription factor, binding to specific genes and activating their transcription into mRNA. The mRNA that is produced is eventually translated into specific proteins. Proteins produced in response to the cortisol signal function in the stress response. For example, some of these proteins aid in elevating glucose levels in the blood, helping an animal to meet the demands of starvation or intense physical activity
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