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How Is Bacterial Gene Regulation Similar To Eukaryotic Gene Regulation?

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Similarities: Bacterial and eukaryotic gene regulation involves the action of protein repressors and protein activators. Cascades of gene regulation in which the activation of one set of genes affects another set of genes takes place in both eukaryotes and bacteria. Regulation of gene expression at the transcriptional level is also common in both types of cells. Both have coordinated expression, although, through different mechanisms. Bacterial genes are often clustered in operons and are coordinately expressed through the synthesis of a single polygenic mRNA. Eukaryotic genes are typically separate, with each containing its own promoter and transcribed on individual mRNAs. Coordinate expression of multiple genes is accomplished through the presence of common [shared] response elements. Genes sharing the same response element will be regulated by the same regulatory factors.

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