Outcomes Of Complement Activation

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Outcomes Of Complement Activation

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1. Stimulation of inflammatory reactions via release proinflammatory mediators, which induce chemotaxis of leukocytes (leading to microbe destruction) & inflammation 2. Opsonization of pathogens by depositing fragments of complement proteins on the pathogens, making them more susceptible to phagocytosis 3. Complement-Mediated Cytolysis, via formation of a Membrane Attack Complex, which can insert itself into bacterial membrane & cause osmotic lysis

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