in drug responses? [X] time of day [O] acidity of urine [O] size of the person [>] All of the above Reason: Pages 139 INCORRECT 2: Select the incorrect statement. [O] Potency is determined by the amount of drug necessary to cause a given effect. [X] A very potent drug often is effective at low doses. [O] Toxicity is not always related to dosage in a simple linear relationship. [>] Toxicity of a drug is unrelated to its potency. Reason: Pages 139-141 CORRECT 3: You have discovered that you require at least 300 mg of aspirin to get any pain relief. Which of the following terms best describes this phenomenon? [O] plateau dose [O] biological half-life [X] threshold dose [O] cumulative effect Reason: Page 147 INCORRECT 4: Select the incorrect statement. [>] There are usually substantial differences in the way males and females respond to drugs. [O] Usually the elderly should be given lower doses than other adults to avoid adverse effects. [O] The condition of pregnancy can increase a woman's vulnerability to drug side effects. [X] A history of hepatitis often results in a longer duration of drug effects and increased likelihood of side effects. Reason: Page 149 INCORRECT 5: Select the incorrect statement concerning psychological dependence. [O] It can occur independent of physical dependence. [O] It often occurs from using drugs with abuse potential. [X] It can cause intense craving and lure former drug abusers back to their drug habits. [>] It causes severe physical discomfort and rebound when drug use is stopped. Reason: Page 154-155 INCORRECT 6: Most drug abusers are single drug users. [X] TRUE [>] FALSE Reason: Page 144 CORRECT 7: Not all drugs can enter the brain once they get into the blood. [X] TRUE [O] FALSE Reason: Page 146 CORRECT 8: The effects of acute and chronic use with the same drug can be different. [X] TRUE [O] FALSE Reason: Page 147 CORRECT 9: Offspring of alcoholics are more likely to develop alcohol dependency than children of non-alcoholic parents. [X] TRUE [O] FALSE